Nalu Peripheral Nerve Stimulation (PNS)
The Nalu Neurostimulation System by Nalu Medical is an advanced peripheral nerve stimulation (PNS) platform designed for patients with chronic focal pain. It combines a remarkably small implantable micro-IPG (implantable pulse generator) with an external, wearable pulse transmitter — providing powerful neuromodulation with minimal surgical burden.
How the Nalu System Works
A micro-sized implantable pulse generator is placed subcutaneously (just under the skin) near the target peripheral nerve. The micro-IPG is one of the smallest neurostimulation implants available and requires only a minor implantation procedure.
Stimulation is delivered wirelessly from an external pulse transmitter (EPT) worn on the body over the implant site. The EPT also charges the micro-IPG wirelessly — eliminating the need for surgical battery replacements. Patients control their stimulation intensity and patterns through a simple handheld device.
Conditions Treated
Nalu PNS is appropriate for patients with chronic pain in specific nerve distributions, including:
- Failed back surgery syndrome — Persistent pain after lumbar or cervical spine surgery
- CRPS (Complex Regional Pain Syndrome) — Targeting affected peripheral nerves
- Chronic limb pain — Including post-amputation and post-traumatic pain
- Post-surgical neuropathic pain — Pain persisting in a specific nerve distribution after surgery
- Peripheral neuropathy — Focal nerve pain not responsive to medications
Key Advantages
Minimally invasive implant — The micro-IPG placement is a minor procedure compared to traditional SCS or larger PNS systems.
No battery surgery — Wireless charging eliminates the need for surgical battery replacements over time.
Targeted therapy — Peripheral nerve stimulation targets the specific nerve responsible for pain, rather than broadly stimulating the spinal cord.
Reversible — The system can be deactivated or removed if needed.
Rechargeable external control — Patients manage therapy through an external wearable, not a surgically implanted controller.
How It Differs from Spinal Cord Stimulation
Spinal cord stimulation (SCS) targets the dorsal columns of the spinal cord and is most effective for diffuse or bilateral pain patterns. Nalu PNS targets individual peripheral nerves and is better suited for focal, unilateral pain in a defined nerve distribution. The two approaches complement each other — some patients benefit from one, others from the other.
Frequently Asked Questions
Is this a permanent implant? The micro-IPG is implanted permanently but can be removed if needed. The external pulse transmitter is worn during therapy sessions and is not implanted.
How long does the implant procedure take? Placement of the micro-IPG typically takes 30–60 minutes under local anesthesia or light sedation, as an outpatient procedure.
Is Nalu PNS covered by insurance? Coverage varies. Our office will verify your specific benefits prior to scheduling.
Contact Us
Call 516-492-3100 to find out whether Nalu peripheral nerve stimulation may be appropriate for your chronic pain condition.