Sphenopalatine Ganglion Block

The sphenopalatine ganglion (SPG) is a cluster of nerve cells located deep in the face behind the nose, carrying autonomic nerve signals implicated in cluster headaches, migraines, and certain facial pain syndromes. An SPG block delivers local anesthetic to this ganglion to interrupt pain signaling.

How SPG Blocks Are Performed

Modern SPG blocks are performed using a minimally invasive transnasal approach — no needles through the face. A thin, flexible catheter is passed through the nostril to the lateral nasal wall, where local anesthetic is delivered to the ganglion through the mucosal surface. The procedure takes only 10–15 minutes and is well-tolerated.

Conditions Treated

Cluster Headaches: SPG blocks are a recognized acute and preventive treatment for cluster headaches — one of the most painful conditions known to medicine. Both abortive (to stop an active attack) and preventive (to reduce attack frequency) protocols are used.

Chronic Migraine: SPG blocks can reduce migraine frequency and severity when used as part of a preventive treatment program.

Trigeminal Neuralgia and Facial Pain: Some patients with refractory facial pain respond to SPG blockade.

Atypical Facial Pain and Sluder's Neuralgia: Pain syndromes involving the SPG region.

What to Expect

The procedure is performed in the office without sedation in most cases. You lie on your back; the catheter is gently inserted through the nostril. You may taste the local anesthetic as it reaches the back of the throat — this is normal and temporary.

Contact Us

Call 516-492-3100 for evaluation of cluster headaches, refractory migraines, or facial pain that may respond to SPG treatment.